Research & development, technologies and products
We develop, produce and market vaccines and antibodies against a range of infectious diseases, focusing strongly–but not exclusively–on unmet medical needs in developing countries and emerging economies. Vaccines play a vital role in protecting against diseases and have contributed significantly to the improvement of global public health in the 21st century. Below we highlight Crucell’s key innovations.
Total revenues and operating income Products continue to show strong growth.
Vaccine doses distributed in 2009.
Crucell vaccines were sold in more than 100 countries in 2009.
|Development stage||Research/ |
|Phase I||Phase II||Phase III||Marketed||Description|
|Quinvaxem®||Fully liquid vaccine for protection against five childhood diseases.|
|Hepavax-Gene®||Recombinant hepatitis B vaccine.|
|Epaxal® Junior||Low dosage aluminum-free hepatitis A vaccine (0.25ml).|
|MoRu-Viraten®||Vaccine for protection against measles and rubella.|
|Epaxal®||Aluminum-free hepatitis A vaccine.|
|Vivotif®||Oral typhoid vaccine.|
|Dukoral®||Only internationally licensed oral vaccine against cholera (and ETEC).|
|Inflexal® V||Virosomal adjuvanted influenza vaccine.|
|Vaccines in development:|
|Flavimun®||Yellow fever vaccine.|
|Seasonal influenza vaccine.1|
|Tuberculosis||Recombinant AdVac®-based tuberculosis vaccine.2|
|Malaria||Recombinant AdVac®-based malaria vaccine.3|
|Ebola and Marburg||Recombinant AdVac®-based Ebola and Marburg vaccine.3|
|HIV||Recombinant AdVac®-based vaccine.4|
|Human monoclonal antibodies in development:|
|Rabies antibody combination||Two human monoclonal antibodies for post-exposure treatment of rabies.5|
|Influenza antibodies||Neutralizing antibody cross reactive against different influenza subtypes including H5 and H1.|
|Hepatitis C antibody combination||Neutralizing monoclonal antibodies across all genotypes tested.|
- Developed by sanofi pasteur using PER.C6®. 2 Partnered with Aeras. 3 Partnered with NIH/NIAID. 4 Partnered with Harvard.
- Partnered with sanofi pasteur.