Crucell 2008
Combating Infectious Diseases
Annual Report and Form 20–F

• What Corporate Social Responsibility means to us
• What we do
• A CSR dilemma
• Crucell on its mission to combat infectious diseases
• Who we work with
• An example: Warm response to cold chain training
• How we do business
• A partnership with customers illustrated
• Crucell's PER.C6^® technology
• How we see our responsibility
• Crucell works in an environment that requires highly skilled employees
• Innovative safety approach
• Beyond legislation for safety
• Environmental impact
• An example: Combining vaccines for a diversity of benefits
• Energy & water consumption
• Economic aspects of our business

An example: Warm response to cold chain training

The cold chain workshops were very well received by our customers and generate tangible loyalty to Crucell and our vaccines, and above all, better vaccine management practices among our customers. Carlo Precali, Regional Director Crucell Latin America

The cold chain is a temperature-controlled distribution process ensuring the quality and extended shelf life of foods and medicines. As part of the clinical good manufacturing practice (cGMP) environment, which regulates all drugs and biologicals, the cold chain has to conform to validated practices enforced by the regulatory authorities. Maintaining the cold chain is especially important – and challenging – when vaccines are being transported to remote clinics in countries with hot climates and poor infrastructure.

During 2008, Crucell’s office in Latin America organized a successful series of workshops designed to enhance knowledge of the cold chain process among our institutional customers in the region. The workshops focused on theoretical and practical concepts for the cold chain handling of vaccines and other medicines in accordance with regulatory requirements.

Crucell conducted the workshops in three different cities of the Andean region: Bogotá in Colombia, Lima in Peru and Quito in Ecuador. Each attracted approximately 80 people who are directly or indirectly involved with the distribution of vaccines in their respective countries. These included national managers of the Expanded Program of Immunization (EPI), local representatives of the Pan American Health Organization (PAHO), and medical doctors and nurses.