R&D Partners & Licensees
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Below you will find a full overview of Crucell’s

R&D partners and licensees

 

Latest update: November 22, 2010

 

Development stages:
Preclinical
Phase I
Phase II
Phase III

                                      

Vaccines

Partner/

Licensee 

Starting

date   

Technology platform             

Area

Development stage

Aeras Global TB Vaccine Foundation

Mar. 2004         

  

PER.C6® + AdVac®     

Tuberculosis

 

Bestewil Holding BV

Jan. 2006

Co-micelles

Influenza

Harvard School of

Medicine

Dec. 2003

AdVac® + Ad5HVR48

HIV

International AIDS

Vaccine Initiative (IAVI)

Sep. 2004

AdVac®

 

HIV

Kimron Veterinary

Institute

 

July 2003

 

PER.C6®

 

West Nile Virus Veterinary

vaccine (avian)

 

Marketed

in Israel

Merck & Co. Inc.

Nov. 1998 

PER.C6®

Undisclosed

vaccines

Merck & Co. Inc.

 

Dec. 2006

 

PER.C6® + AdVac®

 

2 infectious disease areas

 

National Institutes of Health (NIH)

 

Mar. 2002

 

PER.C6® + AdVac®

 

Ebola, lassa and Marburg

 

 

National Institutes of Health (NIH)

 

Mar. 2004

 

PER.C6® + AdVac®

 

Malaria

 

Okairos Srl.

 

Oct. 2006

 

PER.C6®

 

Hepatitis C

 

TapImmune Inc.

 

Nov. 2008

 

PER.C6®

 

Undisclosed vaccine

 

Transgene SA

 

Dec. 2007

 

PER.C6®

 

Undisclosed vaccine

 

Transgene Jan. 2010

PER.C6®

Infectious diseases

Vaxin, Inc.

 

Sep. 2004

 

PER.C6®

 

Alzheimers disease

and veterinary

 

Proteins

Partner/

Licensee

 

Starting date

 

Technology platform

 

Area

 

Development stage

Abraxis Bioscience, LLC. Oct. 2008

PER.C6®

Protein production
Affitech A.S. Nov. 2008

PER.C6®

Undisclosed antibodies
Bioceros B.V. May 2008

STAR®

Portfolio antibodies

Biotecnol S.A. Jan. 2007

PER.C6®

Portfolio antibodies
Cangene Corp. Oct. 2008

PER.C6®

Undisclosed antibodies

Centocor Inc. Dec. 2008

STAR®

Monoclonal antibodies
CSL Ltd. Dec. 2008

PER.C6®

Undisclosed protein
Daiichi Sankyo Co. Ltd. Nov. 2007

PER.C6®

Portfolio antibodies

Ferring International Center SA

May 2005

PER.C6®

Women’s healthcare

Ferring International Center S.A.

Dec. 2005

PER.C6®

Women’s healthcare

Gedeon Richter PLC Nov. 2008

PER.C6®

Undisclosed biopharmaceutical

GlaxoSmithKline

Biologicals SA

Dec. 2008

PER.C6®

Recombinant

protein

IQ Corporation B.V.

Oct. 2005

PER.C6®

Anti-anthrax antibody

LFB Biotechnologies

July 2007

PER.C6®

Undisclosed antibodies

Merus B.V.

Jun. 2004

PER.C6®

Portfolio oligoclonics

MorphoSys A.G.

Aug. 2004

PER.C6®

Portfolio antibodies

MorphoSys A.G. Aug. 2006

PER.C6®

Inflammatory diseases

MorphoSys A.G.

Apr. 2008

PER.C6®

Oncology
NeoPharm Co. Ltd Apr. 2010

PER.C6®

Recombinant proteins and antibodies
Oy Medix Biochema AB Dec. 2009

PER.C6®

Recombinant antibodies   
Patrys Ltd. July. 2009

PER.C6®

Monoclonal antibodies
Patrys Ltd. Feb. 2007

PER.C6®

Undisclosed protein

PR&D Biotech S.A.

Oct. 2007

PER.C6®

Undisclosed protein

ProFibrix B.V. Dec. 2008

PER.C6®

Recombinant fibrinogen

ProFibrix B.V.

Dec. 2008

PER.C6®

Recombinant thrombin
Synthon B.V. Nov. 2008

PER.C6®

Biosimilar protein
Development Center for Biotechnology (Taiwan) Mar. 2007

PER.C6®

Undisclosed proteins

 
Talecris Biotherapeutics Inc. Sep. 2008

PER.C6®

Undisclosed protein

Talecris Biotherapeutics Inc.

Dec. 2008

PER.C6®

Undisclosed proteins

Thrombolytic Science Int. Inc

Oct. 2009 PER.C6®

Undisclosed protein

Yeda R&D Company Ltd

May 2010

PER.C6®

Antibodies against Hepatitis B

Gene Therapy

Partner/

Licensee

Starting date

 

Technology platform

 

Area

 

Development stage

Ark Therapeutics

Jan. 2006

PER.C6®

Portfolio

Broadvector Limited Dec. 2008

PER.C6®

Adenovirus-vectored product

Cancer Research UK Centre Jan. 2010

PER.C6®

Oncology

Merck & Co., Inc.

Nov. 1998

PER.C6®

Portfolio

Momotaro-Gene Inc. Aug. 2009

PER.C6®

Prostate cancer

NeoTropix Inc.

 

Mar. 2004

 

PER.C6®

 

Oncology

 

TapImmune

 

Aug. 2003

 

PER.C6®

 

Portfolio

 

Transgene SA

 

April 2001

 

PER.C6®

 

Portfolio

 

 

Alliances with Manufacturing Contractors

Partner/

Licensee

 

Starting

date

 

Technology platform

 

Development stage

Bioceros Jan. 2009

PER.C6®

Cell line generation services

Biochrom AG

Nov. 2008

PER.C6® /

PERMEXCIS®

Medium development

Cambrex (acquired by Lonza Ltd.)

 

Aug. 2004

 

PER.C6®

 

Medium development

Invitrogen Corp.

June 2003

PER.C6®

Medium development

Eden Biodesign Ltd. Oct. 2010

PER.C6®

Manufacturing services for vaccines and gene therapies
JRH Biosciences Inc. (acquired by Sigma Aldrich Corp.) May 2004

PER.C6®

Medium development recombinant vaccines
KBI Biopharma Jan. 2009

PER.C6®

Cell line generation services

Lonza Verviers Sprl/Lonza Sales Ltd.

Nov. 2008

PER.C6® /

PERMEXCIS®

Medium development

 

SAFC Pharma

Dec. 2001

PER.C6®

Recombinant vaccines & gene therapy products (US)

Sigma-Aldrich Corp.

 

Dec. 2003

 

PER.C6®

 

Medium development

Thermo Fischer Scientific Inc. Dec. 2003

PER.C6®

Medium development

Vivante GMP Solutions Inc. May 2009

PER.C6®

Manufacturing services and gene therapeutics

Genomics

Partner/

Licensee

 

Starting

date

 

Technology platform

 

Area

Galapagos Genomics N.V.

 

June 1999

 

PER.C6®

 

Genomics



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